Stil CLIA Kit for Mouse(Mus musculus) | EIAab.comStil CLIA Kit for Mouse(Mus musculus)

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Stil (Gene name),

SCL-interrupting locus protein homolog (Protein name ), STIL_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Stil(Sil);

Protein name:

SCL-interrupting locus protein homolog;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with PIN1 via its WW domain. This interaction is dependent on Stil mitotic phosphorylation.

Function:

Immediate-early gene. Plays an important role in embryonic development as well as in cellular growth and proliferation; its long-term silencing affects cell survival and cell cycle distribution as well as decreases CDK1 activity correlated with reduced phosphorylation of CDK1. Play a role as a positive regulator of the sonic hedgehog pathway, acting downstream of PTCH1.

Subcellular Location:

Cytoplasm cytosol

Protein Attributes:

Sequence length:

1262

Sequence:

50:

100:

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300:

350:

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450:

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1150:

1200:

1250:

1262:

DVKRLRQLPK | LF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:20460

UniGene:

Mm.3988

String:

Q60988

STRING:

10090.ENSMUSP00000030490

Uniprot:

Q60988

FOR

ELISA Kit for Mouse SCL-interrupting locus protein homolog

Cat.:

E3405h

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Mouse SCL-interrupting locus protein homolog

Cat.:

E3405m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse SCL-interrupting locus protein homolog

Cat.:

U3405m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse SCL-interrupting locus protein homolog

Cat.:

U3405h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse SCL-interrupting locus protein homolog

Cat.:

P3405Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse SCL-interrupting locus protein homolog

Cat.:

P3405Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse SCL-interrupting locus protein homolog

Protein for Mouse SCL-interrupting locus protein homolog

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and characterization of a murine SIL gene."
Collazo-Garcia N. , Scherer P. , Aplan P.D.
Genomics30:506-513(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;FUNCTION
strain: C57BL/6 X CBA.
2.

"Long-range comparison of human and mouse SCL loci: localized regions of sensitivity to restriction endonucleases correspond precisely with peaks of conserved noncoding sequences."
Goettgens B. , Gilbert J.G.R. , Barton L.M. , Grafham D. , Rogers J. , Bentley D.R. , Green A.R.
Genome Res.11:87-97(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1094 AND 449-1262
strain: C57BL/6J.
tissue: Skin.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-957 AND 1056-1262
strain: Czech II.
strain: FVB/N.
tissue: Mammary gland.
5.

"Structural characterization of SIL, a gene frequently disrupted in T-cell acute lymphoblastic leukemia."
Aplan P.D. , Lombardi D.P. , Kirsch I.R.
Mol. Cell. Biol.11:5462-5469(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
6.

"The SIL gene is required for mouse embryonic axial development and left-right specification."
Izraeli S. , Lowe L.A. , Bertness V.L. , Good D.J. , Dorward D.W. , Kirsch I.R. , Kuehn M.R.
Nature399:691-694(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
7.

"Genetic evidence that Sil is required for the Sonic Hedgehog response pathway."
Izraeli S. , Lowe L.A. , Bertness V.L. , Campaner S. , Hahn H. , Kirsch I.R. , Kuehn M.R.
Genesis31:72-77(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
8.

"Sil phosphorylation in a Pin1 binding domain affects the duration of the spindle checkpoint."
Campaner S. , Kaldis P. , Izraeli S. , Kirsch I.R.
Mol. Cell. Biol.25:6660-6672(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PIN1;REGION;MUTAGENESIS OF THR-574; SER-643; SER-656; SER-664; THR-686; SER-699 AND SER-760;PHOSPHORYLATION

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